First-in-class XOFLUZA stops the flu at its source 1,14

1-dose XOFLUZA works differently by targeting the flu at its source to stop viral replication. 1

Watch the XOFLUZA mechanism of action

M2 ion channel blockers/adamantanes target viral uncoating in stage 2; however, they are no longer recommended by the CDC due to high resistance. 14,17

Neuraminidase inhibitors (NAIs), such as oseltamivir, target the last stage of the viral life cycle: viral release. This prevents the already replicated virus from leaving the host cell. 14,16

XOFLUZA works differently by targeting the flu earlier at its source, in stage 3. XOFLUZA inhibits influenza-specific polymerase acidic endonuclease to prevent viral replication. 1,16

XOFLUZA safety profile

XOFLUZA was as safe and well-tolerated as placebo in clinical trials. 1