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Frequently Asked Questions

Getting My XOFLUZA Prescription

The first 48 hours are critical to fighting the flu with antivirals. When symptoms first appear ask if XOFLUZA is right for you by:

  • contacting your doctor
  • visiting your nearest urgent care facility

Virtual care is a way patients and doctors can connect through digital tools like computers or smartphones. It is also known as telemedicine or telehealth.

Contact your insurance or employer to find out what virtual care options may be covered by your health plan or you may be able to find virtual care options at Telehealth.hhs.gov.

With the XOFLUZA coupon, eligible patients may pay as little as $30 for their XOFLUZA prescription, up to $60 off. Terms and conditions apply.

One-dose XOFLUZA is available through retail pharmacies. Call ahead to confirm availability at a location near you.

The first 48 hours are critical to fighting the flu. Have your prescription filled right away.

Other Common Questions

COVID-19 and the flu are two different types of illnesses that can be potentially life-threatening. It is difficult to tell the difference between them because some of the symptoms can be similar. If you have flu-like symptoms, help protect yourself and others by contacting your doctor. If it is the flu, you may be able to treat it with prescription XOFLUZA.

To learn more about COVID-19, visit the official website of the Centers for Disease Control and Prevention (CDC) at CDC.gov.*

*The CDC does not endorse private products, services, or enterprises. Links to CDC.gov are provided for informational purposes only. 

According to the CDC, patients who are at higher risk for severe complications from COVID-19 or the flu include older adults, those who are pregnant, and people with certain underlying medical conditions (including infants and children).*

To learn more about COVID-19, visit the official website of the Centers for Disease Control and Prevention (CDC) at CDC.gov.*

*The CDC does not endorse private products, services, or enterprises. Links to CDC.gov are provided for informational purposes only.

It can be tough to tell the difference between cold and flu symptoms. Flu symptoms often come on fast and include fever, aches and chills.
Learn more about the difference between a cold and the flu.

Yes. Even if you received the flu vaccine and have still come down with the flu, you can still treat it with prescription one-dose XOFLUZA.

Ask your doctor about one-dose XOFLUZA when flu symptoms first appear. The first 48 hours are critical to fighting the flu with XOFLUZA.

XOFLUZA treats the flu in one dose with one tablet.
Take XOFLUZA with or without food.

  • Do not take XOFLUZA with dairy products, calcium-fortified beverages, laxatives, antacids or oral supplements containing iron, zinc, selenium, calcium or magnesium.

One-dose XOFLUZA helps protect you and your family members aged 5 years and older from getting the flu. XOFLUZA helps lower your chances of getting the flu by 87% after being exposed to someone who has the flu, compared with placebo. If a family member has been exposed to the flu, you need to act fast because the window for treatment is short.

What is XOFLUZA?

XOFLUZA is a prescription medicine used to:

  • treat the flu (influenza) in people who have flu symptoms for no more than 48 hours and who are:
    • otherwise healthy adults and children 5 years of age and older, or
    • adults and children 12 years of age and older who are at high risk of developing problems from the flu.
  • prevent the flu in people 5 years of age and older following contact with a person who has the flu (post-exposure prophylaxis).

XOFLUZA does not treat or prevent illness that is caused by infections other than the influenza virus.

 

XOFLUZA does not prevent bacterial infections that may happen with the flu.

 

It is not known if XOFLUZA is safe and effective for the treatment and prevention of the flu in children less than 5 years of age. XOFLUZA is not for use in children less than 5 years of age.

Important Safety Information

Who should not take XOFLUZA?

  • Do not take XOFLUZA if you are allergic to baloxavir marboxil or any of the ingredients in XOFLUZA.

 

What should I tell my healthcare provider before using XOFLUZA?

  • Tell your healthcare provider about all of your medical conditions, including if you are:
    • Pregnant or plan to become pregnant. It is not known if XOFLUZA can harm your unborn baby.
    • Breastfeeding or plan to breastfeed. It is not known if XOFLUZA passes into your breast milk.
  • Talk to your healthcare provider before you receive a live flu vaccine after taking XOFLUZA.
  • Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, antacids, laxatives, vitamins, and herbal supplements.


What are the possible side effects of XOFLUZA?
Serious side effects may include

  • Allergic reaction. Get emergency medical help right away if you develop any of the following signs or symptoms of an allergic reaction:
    • trouble breathing
    • skin rash, hives or blisters
    • swelling of your face, throat or mouth
    • dizziness or lightheadedness

The most common side effects of XOFLUZA for treatment of the flu in adults and adolescents (12 years of age and older) were diarrhea, bronchitis, nausea, sinusitis, and headache.

 

The most common side effects of XOFLUZA for treatment of the flu in children (5 years of age to less than 12 years of age) were diarrhea and vomiting.  

 

These are not all the possible side effects of XOFLUZA. Call your healthcare provider for medical advice about side effects.

XOFLUZA is not effective in treating or preventing infections other than influenza. Other kinds of infections can have symptoms like those of the flu or occur along with flu and may need different kinds of treatment. Tell your healthcare provider if you feel worse or develop new symptoms during or after treatment with XOFLUZA or if your flu symptoms do not start to get better.


You are encouraged to report side effects to Genentech by calling 1-888-835-2555 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088.

Please see full Prescribing Information, including Patient Product Information.