For US Healthcare Professionals

What is XOFLUZA?

TREAT THE FLU

How fast does XOFLUZA work?

The CDC recommends treating the flu with a prescription medication within the first 48 hours of experiencing symptoms*

Children between 5 and 11 years old can feel better in just over 5.5 days†

One-dose XOFLUZA should be taken within the first 48 hours of experiencing flu symptoms.

†On average, patients aged 5 to less than 12 years felt better in 5.75 days vs 5.25 days with oseltamivir.

Patients aged 12 years and older can feel better in just over 2 days‡

Without prescription medication, flu symptoms can last up to a week. Patients aged 12 years and older taking one-dose XOFLUZA felt better in an average of 2.3 days versus 3.3 days with placebo.

‡On average, patients aged 12 years and older felt better in 2.3 days vs 3.3 days with placebo.

HELP PREVENT THE FLU

One-dose XOFLUZA can help prevent you from getting the flu

XOFLUZA helps protect you and your family members aged 5 years and older from getting the flu. XOFLUZA may help lower your chances of getting the flu by 87% after being exposed to someone who has the flu, compared with placebo. If a family member aged 5 years and older has been exposed to the flu, you need to act fast because the window for treatment is short.

TABLET SIZE

One-dose XOFLUZA tablet size

A small, white, oval pill XOFLUXA 40 mg

XOFLUZA 40 mg

11 mm = 0.43 inches

A small white breath mint

Breath Mint

~12 mm = 0.5 inches

A small, white, oblong pill XOFLUXA 80 mg

XOFLUZA 80 mg

16 mm = 0.63 inches

Not actual size. Both tablet sizes are similar to that of a small breath mint.

Over-the-counter medicines only treat flu symptoms, but prescription one-dose XOFLUZA attacks the flu virus at its source.

XOFLUZA is a generally well-tolerated flu medication

The most common side effects of XOFLUZA for treatment of the flu in adults and adolescents (12 years of age and older) were diarrhea, bronchitis, nausea, sinusitis, and headache. The most common side effects of XOFLUZA for treatment of the flu in children (5 years of age to less than 12 years of age) were diarrhea and vomiting.

See potential side effects

*Source: Centers for Disease Control and Prevention (CDC). The CDC does not endorse private products, services, or enterprises. The content provided is for informational purposes only. Find the latest at CDC.gov.

THE CDC RECOMMENDS TREATING THE FLU IN THE FIRST 48 HOURS OF SYMPTOMS

Don't wait

When the flu hits, act fast. You can talk to a doctor without even leaving the house.

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No need to travel

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Avoid spreading illness

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Frequently asked questions

With the XOFLUZA coupon, eligible patients may pay as little as $35 for their XOFLUZA prescription, up to $70 off. Terms and conditions apply.

Download coupon now

Once you have your prescription, you can get XOFLUZA through retail pharmacies online or in-store.

Find XOFLUZA

Yes. Even if you received the flu vaccine and have still come down with the flu, you can still treat it with one-dose, prescription XOFLUZA. Let your doctor know if you have received a live flu vaccine within the past 2 weeks.

Learn about XOFLUZA

Ask your doctor about one-dose XOFLUZA when flu symptoms first appear. The first 48 hours are critical to fighting the flu with XOFLUZA.

Learn about one-dose XOFLUZA

One-dose XOFLUZA helps protect you and your family members aged 5 years and older from getting the flu. XOFLUZA may help lower your chances of getting the flu by 87% after being exposed to someone who has the flu, compared with placebo. If a family member has been exposed to the flu, you need to act fast because the window for treatment is short.

Learn about one-dose XOFLUZA

Important Safety Information & Indication

What is XOFLUZA?

XOFLUZA is a prescription medicine used to:

  • treat the flu (influenza) in people 5 years of age and older who have flu symptoms for no more than 48 hours and who are:
    • otherwise healthy or
    • at high risk of developing problems from the flu.
  • prevent the flu in people 5 years of age and older following contact with a person who has the flu (post-exposure prophylaxis).

XOFLUZA does not treat or prevent illness that is caused by infections other than the influenza virus.
 

XOFLUZA does not prevent bacterial infections that may happen with the flu.
 

It is not known if XOFLUZA is safe and effective for the treatment and prevention of the flu in children less than 5 years of age. XOFLUZA is not for use in children less than 5 years of age.

 

Important Safety Information

Who should not take XOFLUZA?

  • Do not take XOFLUZA if you are allergic to baloxavir marboxil or any of the ingredients in XOFLUZA.

What should I tell my healthcare provider before using XOFLUZA?

  • Tell your healthcare provider about all of your medical conditions, including if you are:
    • Pregnant or plan to become pregnant. It is not known if XOFLUZA can harm your unborn baby.
    • Breastfeeding or plan to breastfeed. It is not known if XOFLUZA passes into your breast milk.
  • Talk to your healthcare provider before you receive a live flu vaccine after taking XOFLUZA.
  • Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, antacids, laxatives, vitamins, and herbal supplements.

What are the possible side effects of XOFLUZA?
Serious side effects may include

  • Allergic reaction. Get emergency medical help right away if you develop any of the following signs or symptoms of an allergic reaction:
    • trouble breathing
    • skin rash, hives or blisters
    • swelling of your face, throat or mouth
    • dizziness or lightheadedness

The most common side effects of XOFLUZA for treatment of the flu in adults and adolescents (12 years of age and older) were diarrhea, bronchitis, nausea, sinusitis, and headache.
 

The most common side effects of XOFLUZA for treatment of the flu in children (5 years of age to less than 12 years of age) were diarrhea and vomiting.
 

These are not all the possible side effects of XOFLUZA. Call your healthcare provider for medical advice about side effects.
 

XOFLUZA is not effective in treating or preventing infections other than influenza. Other kinds of infections can have symptoms like those of the flu or occur along with flu and may need different kinds of treatment. Tell your healthcare provider if you feel worse or develop new symptoms during or after treatment with XOFLUZA or if your flu symptoms do not start to get better.
 

You are encouraged to report side effects to Genentech by calling 1-888-835-2555 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088.

Please see full Prescribing Information, including Patient Product Information.

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